Increased filaggrin expression in oral lichenoid lesions: is this cause or effect?
نویسندگان
چکیده
منابع مشابه
Oral Lichen Planus or Oral Lichenoid Reaction? A Literature Review
Background and Aim: Oral lichen planus (OLP) is a chronic, inflammatory, T-cell-mediated autoimmune oral mucosal disease. Oral lichenoid lesions develop as a type IV hypersensitivity reaction. Both of these entities are potential precancerous conditions; this adds to their clinical significance. The purpose of this literature review was to detect the similarities and the differences of these le...
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Toll-like receptors (TLRs) and nuclear factor-κB (NF-κB) in keratinocytes play an important role in dermatological autoimmune diseases. Tumour suppressor protein p53 regulates TLR expression. The aim of this study was to compare the expression of TLR1-TLR10, p53 and NF-κB in patients with oral lichenoid disease (OLD) with healthy mucosa. Oral mucosal biopsies from 24 patients with OLD and 26 he...
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Oral lichenoid lesions (OLLs) are a diverse group of disorders that may be attributed to an autoimmune etiology, underlying systemic disease, or in association with an identifiable causative agent, such as a medication, food product, or dental material. OLLs commonly present with striae, erythema, and/or ulceration on affected oral mucosa and can be symptomatic. The aim of this report is to des...
متن کاملPrevalence of Anti Hyperglycemic Agents -Associated Oral Lichenoid Lesions in Type 2 Diabetes Mellitus Patients
Objective: This study aimed to estimate the prevalence of lichenoid reactions to Anti Hyperglycemic Agents. Materials and Methods: In this cross-sectional descriptive and analytic study, we examined the oral mucosa of 411 patients at the age of 29 to 85 in 3 groups who consumed various antihyperglycemic agents. Results: In overall, 31 patients had lichenoid reactions (12 patients taking glibe...
متن کاملExpression of COX-2 and bcl-2 in oral lichen planus lesions and lichenoid reactions
UNLABELLED Oral lichen planus and lichenoid reactions are autoimmune type inflammatory conditions of the oral mucosa with similar clinical and histological characteristics. Recent data suggest that oral lichenoid reactions (OLR) present a greater percentage of malignant transformation than oral lichen planus (OLP). OBJECTIVE To compare the expression of bcl-2 and COX-2 in OLP and OLR. METHO...
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ژورنال
عنوان ژورنال: Journal of the European Academy of Dermatology and Venereology
سال: 2017
ISSN: 0926-9959
DOI: 10.1111/jdv.14265